Osteon microneedle biosensing patch

Predict fractures.
Forecast OA flares.

The first continuous biomarker monitor for bone and joint health. Real-time ISF tracking through a painless microneedle wearable to catch degradation years before a DEXA scan.

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The Problem

Managing bone disease with an annual DEXA scan is like managing diabetes by checking glucose twice a year.

Current diagnostics deliver snapshots — a single DEXA every 1–2 years and sporadic blood panels. Dynamic bone turnover cycles and inflammatory flares are missed entirely between visits.

0M+

Patients affected globally

by osteoporosis and osteoarthritis

1–2 yrs

Between DEXA scans

Missing critical bone turnover data

Zero

Home visibility

Into bone metabolism or OA flares

CLINICAL PRECISION

Wear the patch,
decode your skeleton.

Track specialized biomarkers continuously to catch degradation years before a DEXA scan can detect irreversible bone loss.

BONE RESORPTION

0pg/mL

C-Telopeptide of Type I Collagen

Tracks osteoclast-driven bone breakdown in real time. Picomolar-level electrochemical immunosensing detects resorption spikes before they become irreversible bone loss.

BONE FORMATION

0ng/mL

Procollagen Type I N-Terminal Propeptide

Measures osteoblast activity and new bone synthesis. Sandwich ELISA-on-chip architecture with HRP catalysis detects formation rates to balance against resorption.

INFLAMMATION

0pg/mL

Interleukin-6

Electrochemical aptamer-based sensing monitors systemic inflammation. Time-series anomaly detection enables 24–48 hour OA flare prediction for preemptive intervention.

MINERAL BALANCE

0mmol/L

Ionized Calcium

Continuous ion-selective electrode monitoring tracks calcium flux critical to bone mineralization, muscle function, and nerve signaling.

The Platform

Three components.
One continuous system.

COMPLETE ECOSYSTEM

Full-Stack Biotelemetry

A seamless integration of medical-grade hardware, electrochemical processing, and AI translation.

ISFPatchReaderCloud AI
Osteon platform
01

Disposable Patch

10–14 day wear

Medical-grade microneedle biosensing array for painless, continuous ISF extraction at just 2mm depth.

  • Painless 2mm microneedles
  • Multiplex sensors
  • NFC data transfer
  • Water-resistant
02

Reusable Reader

Magnetic snap-on

Multi-channel potentiostat processes raw electrochemical signals, then transmits via BLE to your device.

  • Multi-channel potentiostat
  • BLE 5.3 transceiver
  • Li-Po battery
  • Magnetic connector
03

App & Dashboard

AI-powered insights

Translates complex biochemical data into intuitive health metrics and secure clinician remote monitoring.

  • Bone health score
  • Predictive AI alerts
  • Lifestyle integration
  • Clinician dashboard

Clinical-Grade

Picomolar detection limits

2mm

Painless microneedle depth

4 Biomarkers

Real-time ISF sensing

10–14 days

Continuous wear per patch

Get early access to the future of bone health monitoring.

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